Biacore™ X100

The Biacore™ X100 from GE Healthcare is an automated and versatile system for comprehensive, label-free analysis and characterization of biomolecular interactions in real-time. The system contains all the key functionalities needed for day-to-day molecular interaction research with the purpose of understanding protein function and biological mechanisms.

The Biacore™ X100 can provide real-time insights into protein function & biological mechanisms; examine kinetics, affinity, specificity and concentration analysis in one system; and help select promising molecules that could be novel targets for research use, diagnostics, or therapy.

Applications

  • Structural-functional studies
  • Pathway analysis
  • Biomarker discovery and validation
  • Drug target identification and validation
  • Assay development
  • Analysis of small molecule interactions
  • Antibody analysis

Measurement options

  • Kinetics
  • Affinity
  • Specificity
  • Concentration

Specifications and features

  • Detection technology: surface plasmon resonance (SPR) biosensor
  • Sample: low molecular weight drug candidates to high molecular weight particles (proteins, DNA, RNA, polysaccharides, lipids, cells and viruses) in various sample environments
  • Maximum capacity: 15 samples
  • Minimum sample volume: 25 to 120 μL
  • Molecular weight detection: as low as 100 Da
  • Association rate constant (ka): 103 to 107 M-1s-1